Implication for health policy/practice/research/medical education:
Lecithin-cholesterol acyltransferase (LCAT) deficient patients may present with renal disease only even with normal high-density lipoprotein cholesterol (HDL-C) levels. Hence, it needs high index of suspicion for LCAT deficiency when renal biopsy is suggestive of lamellar foamy deposits in mesangium and capillary walls even if serum HDL-C levels are normal.
Please cite this paper as: Balwani MR, Ghodela VA, Kute VB, Shah PR, Patel HV, Gera DN, et al. An unusual presentation of LCAT deficiency as nephrotic syndrome with normal serum HDL-C level. J Nephropharmacol. 2017;6(1):23-26.