eISSN: 2345-4202  
J Nephropharmacol. 2018;7(1):3-5.


Future directions in the treatment of BK virus nephropathy

Wisit Cheungpasitporn 1 * , Charat Thongprayoon 2, Supavit Chesdachai 3,4, Jackrapong Bruminhent 4

1 Department of Internal Medicine, Division of Nephrology, University of Mississippi Medical Center, Jackson, Mississippi, USA
2 Department of Internal Medicine, Bassett Medical Center, Cooperstown, NY, USA
3 Department of Medicine, University of Minnesota, Minnesota, USA
4 Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand
*Corresponding author: Wisit Cheungpasitporn MD, Email: Email: wcheungpasitporn@gmail.com

Implication for health policy/practice/research/medical education:

BK polyomavirus-associated nephropathy (BKVAN) is an important cause of allograft renal dysfunction after kidney transplantation. Recent evidence has suggested associations of BK infection with urological malignancies and the development of de novo donor specific antibody (DSA). Despite recent advances in kidney transplantation knowledges, management of BKVAN has remained challenges. Recent evidence has suggested that BK-specific T-cell responses, but not neutralizing antibodies, is important in clearance of BK viremia. In this article, we present future directions in prevention and treatment of BKVAN.

Please cite this paper as: Cheungpasitporn W, Thongprayoon C, Chesdachai S, Bruminhent J. Future directions in the treatment of BK virus nephropathy. J Nephropharmacol. 2018;7(1):3-5. DOI: 10.15171/npj.2018.02. 



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Submitted: 14 Apr 2017

Accepted: 23 Aug 2017
First published online: 30 Nov 2017
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