Implication for health policy/practice/research/medical education:
Over the last several decades, mass poisonings of diethylene glycol (DEG), usually ingested as an unintended component of
pharmaceutical preparations, have occurred in Nigeria, especially affecting children with nearly 100% mortality outcomes.
The unavailability of toxicology laboratory testing facilities often translates to non-diagnosis and therefore inappropriate
management of these patients. In this case analysis, we propose the utility and monitoring of serial values of commonly available
blood test parameters such as serum bicarbonate and anion gap, blood ABG pH and CO2 values, together with the use of serum
osmolality gap to expedite early and appropriate treatment of such cases. Moreover, it remains the obligate duty of the various
governments in these countries to ensure the availability of requisitely necessary ancillary laboratory testing services in their
areas of jurisdiction.
Please cite this paper as: Onuigbo MA, Samuel E, Agbasi N, Zurob A. Proposed laboratory surrogate markers for the
management of acute kidney injury in ethylene glycol poisoning in resource-challenged countries; a Mayo Clinic Health System,
Wisconsin, case analysis. J Nephropharmacol. 2018;7(1):46-49. DOI: 10.15171/npj.2018.11.