Introduction: Urinary tract infection is one of the most common infections. About 10% of people
experience it in their lifetime. Due to the significant increase in antibiotic resistance and the
unpredictability of antibiotic susceptibility of pathogens, the availability of antibiotic susceptibility
testing results can be useful in the selection of the antibiotics based on the type and pattern of
antibiotic resistance of the pathogen.
Objectives: The aim of this study was to determine the antibiotic resistance pattern of bacteria
producing urinary tract infection in Sanandaj, Iran.
Materials and Methods: This cross-sectional study was performed on 3126 urinary samples from
Tohid hospital in Sanandaj University of medical sciences in 2017. The urine specimens were
cultured on EBM (Eosin Methylene Blue) and blood agar media. Kirby-Bauer’s standard disk
diffusion method was applied to test the susceptibility of the drug for Mueller-Hinton culture agar
plates. The results were extracted based on the criteria of CLSL (Clinical and Laboratory Standards
Results: In the study of the samples, the results of 708 cultures (22.64%) were positive. Among
the urinary pathogens, Escherichia coli with 291 cases (41/10%) was the most common isolated
bacteria. According to the results of antibiogram, the highest antibiotic resistance was observed
for cefixime (92.51%), ceftriaxone (52.54%) and cotrimoxazole (45.48%). The highest antibiotic
sensitivity was observed for imipenem (96.11%), nitrofurantoin (91.67%) and ceftazidime (88.28%).
Conclusion: According to this study, the highest antibiotic resistance was observed with cefixime,
ceftriaxone and cotrimoxazole that these drugs are not recommended as the first line of antibiotic
therapy. On the other hand, the highest antibiotic susceptibility was observed with Imipenem,
nitrofurantoin and ceftazidime, which should be considered in the treatment of urinary tract