eISSN: 2345-4202  
J Nephropharmacol. 2019;8(2):25-25.


Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients

Amirhesam Alirezaei 1 * ORCiD, Nilofar Massoudi 2, Elham Zare 3 * , Nima Taheri 3

1 Urology and Nephrology Research Center, Shahid Modarres Hospital, Shahid-Beheshti University of Medical Sciences, Tehran, Iran
2 Critical Care Quality Improvement Research Center at Shahid Modarres Hospital, Department of Anaesthesiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Department of Internal Medicine, Shahid-Beheshti University of Medical Sciences, Tehran, Iran


Introduction: Continuous renal replacement therapy (CRRT) is the gold standard renal replacement therapy (RRT) for hemodynamically unstable patients.

Objectives: To study the characteristics and survival of patients undergoing CRRT in Iran.

Patients and Methods: This is a retrospective study conducted on 58 patients indicated for CRRT at the Shahid-Modarres hospital of Tehran during 2016-2017. Gender, age, underlying diseases, comorbidities, history of surgery, dialysis indication, and survival were gathered by reviewing patients’ medical records. The data was analyzed in SPSS version 21.

Results: Sepsis constituted the most common underlying condition at admission. Overall, continuous venovenous hemodialysis (CVVHD) was performed in 72.4% of the patients. Diabetes and hypertension were the most common causes leading to RRT. The most common indication for CRRT was unstable hemodynamic condition. The patients were most frequently referred from ICU (34.5%), emergency department (20.7%), and CCU (15.5%).

Conclusion: We here reviewed the characteristics of hemodynamically unstable patients undergoing CRRT. Our findings can help to understand the most important indications for CRRT and to standardize CRRT practice in Iran.

Implication for health policy/practice/research/medical education:

In a study on 58 patients who underwent CRRT at the Shahid Modarres hospital of Tehran, the most common modality was CVVHD and the most indication of doing CRRT was unstability of hemodynamic condition.

Please cite this paper as: Alirezaei AH, Massoudi N, Zare E, Taheri N. Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients. J Nephropharmacol. 2019;8(2):e25. DOI: 10.15171/ npj.2019.25

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Submitted: 17 Mar 2019

Accepted: 01 Jun 2019
First published online: 29 May 2019
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