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ePublished: 01 Jan 2013
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J Nephropharmacol. 2013;2(1): 3-4.
  Abstract View: 1236
  PDF Download: 1054

Brief Communication

Parathyroid hormone in renal transplanted recipients; a single center study

Hamid Nasri 1, Mahmoud Rafieian-Kopaei 2 *

1 Department of Internal Medicine, Shahrekord University of Medical Sciences, Iran
2 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding author: Prof. Mahmoud Rafieian-Kopaei, Medical Plants Research Center, Shahrekord University of Medical Sciences, Sharekord, Iran. rafieian@yahoo.com

Abstract

This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of 44±12 years. In this study, mean iPTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of iPTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous findings, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and Vitamin D analogues, which may suppress parathyroid hormone secretion.
Keywords: Parathormone, Transplantation, Parathyroid gland

Implication for health policy/practice/research/medical education:

In a study on 72 kidney-transplanted persons with mean ages of 44±12 years. The mean intact PTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of intact PTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous publications, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and vitamin D analogues, which may suppress parathyroid hormone secretion.

Please cite this paper as: Nasri H, Rafieian-Kopaei M. Parathyroid hormone in renal transplanted recipients;a single center study. J Nephropharmacol 2013; 2(1): 3-4.

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