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ePublished: 01 Jan 2015
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J Nephropharmacol. 2015;4(1): 1-3.
  Abstract View: 1093
  PDF Download: 916

Editorial

Suggestions for attenuation of renal ischemia reperfusion injury based on mechanisms involved in epithelial cells damages

Majid Tavafi 1 *

1 Department of Anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran
*Corresponding author: Majid Tavafi, E-mail: mtavafi@yahoo.com, Tavafi.m@lums.ac.ir
Keywords: Ischemia, Reperfusion, Kidney, Proximal tubules

Implication for health policy/practice/research/medical education:

Major renal injuries follow ischemia reperfusion take place in two steps: one, ischemia (hypoxia) that induce ATP depletion and leads to epithelial tubular cells or endothelial cells injuries; and second, reperfusion that leads to oxidative stress, nitrosative stress and inflammation.

Please cite this paper as: Tavafi M. Suggestions for attenuation of renal ischemia reperfusion injury based on mechanisms involved in epithelial cells damages. J Nephropharmacol 2015; 4(1): 1-3.

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