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Submitted: 05 May 2019
Accepted: 09 Jan 2019
First published online: 28 Feb 2019
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J Nephropharmacol. 2019;8(2): e18.
doi: 10.15171/npj.2019.18
  Abstract View: 140
  PDF Download: 169

Mini-Review

Antioxidant therapy to improve or resolve atherosclerosis; new hopes and current trends

Banafsheh Yalameha * ORCID logo

1 Department of Biochemistry, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
*Corresponding author: Banafsheh Yalameham Email: Email: Yalameha.b7@gmail.com

Abstract

Atherosclerosis is a chronic inflammatory disease occurring in arterial wall over many decades, often leading to acute cardiovascular event. The different mechanisms are involved in the development of this disease. Oxidative stress process is recognized as an important factor for initiation and progression of atherosclerosis. Many therapeutic approaches exist for controlling, preventing, and treating the disease. Antioxidants are the main compounds that inhibit oxidative stress by oxidation of radical free and including protective effect against cardiovascular disease like atherosclerosis. Recently, several drugs about novel perspectives have been discovered which can improve lipid profiles. This review outlines the anti-atherosclerotic property of antioxidants in prevention and improvement atherosclerosis and its new hopes.
Keywords: Atherosclerosis, Antioxidant, Cardiovascular disease, Coronary artery disease, Oxidative stress, Insulin resistance

Implication for health policy/practice/research/medical education:

Antioxidant therapy can be useful in improving and treatment of atherosclerosis while further research on the issue is still required to extend our knowledge.

Please cite this paper as: Yalameha B. Antioxidant therapy to improve or resolve atherosclerosis; new hopes and current trends. J Nephropharmacol. 2019;8(2):e05. DOI: 10.15171/npj.2019.18

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