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Submitted: 30 Apr 2018
Accepted: 09 Jul 2018
First published online: 23 Aug 2019
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J Nephropharmacol. 2020;9(1): ee07.
doi: 10.15171/npj.2020.07
  Abstract View: 74
  PDF Download: 84

Original

Association of serum magnesium level with resistant hyperlipidemia in diabetic and hypertensive patients

Pardis Kaveh 1 ORCID logo, Afsaneh Malekpour Tehrani 2, Saeid Mardani 1 * ORCID logo

1 Departments of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Social Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding author: Saeid Mardani, Email; Email: dr_s_mardani@yahoo.com

Abstract

Introduction: Both diabetes mellitus and hypertension are aspects of metabolic syndrome.

Objectives: The aim of this study was to determine the relationship between serum magnesium level with resistant hyperlipidemia in a group of diabetic and hypertensive patients.

Patients and Methods: The present cross-sectional study was carried out on 90 hypertensive and diabetic patients who referred to outpatient university clinic in Shahrekord (45 hypertensive and 45 diabetic patients). Included patients had high triglyceride levels despite 8 weeks of treatment with lipid-lowering agents.

Results: There was an inverse significant relationship between serum magnesium and triglyceride levels in diabetic patients (P=0.002, r=-0.458), however, this correlation was not significant in hypertensive patients (P=0.754, r=0.048).

Conclusion: This study showed, serum magnesium may affect triglycerides levels in diabetic patients, however, our finding requires further investigation with larger population.

Keywords: Hypertension, Hyperlipidemia, Diabetes mellitus, Triglyceride

Implication for health policy/practice/research/medical education:

in a study on 90 hypertensive and diabetic patients (45 hypertensive and 45 diabetic patients), we found, an inverse significant relationship between serum magnesium and triglyceride level in diabetic patients (P = 0.002, r = -0.458). Our study showed that serum magnesium may affect triglycerides levels in diabetic patients.

Please cite this paper as: Kaveh P, Malekpour Tehrani A, Mardani S. Association of serum magnesium level with resistant hyperlipidemia in diabetic and hypertensive patients. J Nephropharmacol. 2020;9(1):e07. DOI: 10.15171/npj.2020.07.

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