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Submitted: 05 Aug 2019
Accepted: 19 Sep 2019
ePublished: 01 Nov 2019
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J Nephropharmacol. 2020;9(2): e18.
doi: 10.34172/npj.2020.18
  Abstract View: 36
  PDF Download: 19

Original

The association of serum magnesium with serum triglyceride and cholesterol levels in hemodialysis patients

Milad Fooladgar 1 ORCID logo, Saied Mardani 1 * , Leyla Hedayati Zafarghand 2 ORCID logo

1 Department of Internal Medicine, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Department of Internal Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding author: Saeid Mardani, Email; dr_s_mardani@yahoo.com

Abstract

Introduction: Dysregulated lipid profile has been described in patients with chronic renal failure.

Objectives: In the present study, we investigated the association of serum magnesium level with serum triglyceride and cholesterol levels in a group of hemodialysis individuals.

Patients and Methods: This cross-sectional study was carried out on hemodialysis patients referred to the Hajar hospital of Shahrekord (2015). Patients who have been on hemodialysis for at least three months and had a stable condition for the last two months were recruited. Serum levels of magnesium, cholesterol, and triglyceride were measured, and the data was analyzed.

Results: Of 52 patients, 61.5% were males. The mean age of the patients was 60.17 ± 48.70 (range; 13-78) years and the mean dialysis duration was 44.39 ± 05.52 months. Serum magnesium was inversely and insignificantly correlated with serum cholesterol and triglyceride levels. Serum magnesium was significantly associated with serum albumin and parathormone.

Conclusion: We found non-significant and inverse correlations of serum magnesium with serum cholesterol and triglyceride levels. The association between serum magnesium and dyslipidemia is contradictory, and further studies are required to divulge the role of other contributing factors.

Keywords: Lipid, Magnesium, Hemodialysis

Implication for health policy/practice/research/medical education:

In an investigation on 52 hemodialysis individuals, we found, non-significant and inverse correlations of serum magnesium with serum cholesterol and triglyceride levels. The association between serum magnesium and dyslipidemia is contradictory, and further studies are required to divulge the role of other contributing factors.

Please cite this paper as: Fooladgar M, Mardani S, Hedayati Zafarghandi L. The association of serum magnesium with serum triglyceride and cholesterol levels in hemodialysis patients. J Nephropharmacol. 2020;9(2):e18. DOI: 10.34172/npj.2020.18

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