Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 6 2 2017 04 01 Impact of a designed isotonic exercise program on pain intensity of muscle cramps in legs of patients undergoing hemodialysis; a randomized clinical trial 85 89 10.15171/npj.2017.10 EN Mahdi Poornazari Khadijeh Dehghani Sara Shahbazi Firooz Khaledi Sardashti Journal Article 10.15171/npj.2017.10 2017 01 19 2017 04 24 Introduction: Pain due to muscle cramp is a common complication during hemodialysis. Studies have shown that exercise can reduce pain and fatigue through reduction of muscle stiffness and sensitivity, and improvement blood flow.