Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 7 2 2018 05 20 Impact of vitamin D deficiency on health with regard to kidney disease; an updated mini-review 55 60 10.15171/npj.2018.13 EN Nozar Dorestan Sara Bahadoram Mohammad Bahadoram Mohammadreza Khosravi Mohammad Davoodi Ali Hasanpour Dehkordi Zaher Khazaei Masoud Amiri Journal Article 10.15171/npj.2018.13 2017 11 20 2018 02 13 Vitamin D or cholecalciferol, as a steroidal hormone, regulates the calcium homeostasis, and bone formation with reabsorption through kidneys, parathyroid glands and bowel. There are at least 800 human genes connected with vitamin D. Previous research has confirmed the relationship between vitamin D and colorectal cancers, infections, heart diseases, multiple sclerosis (MS), bone disorders, inflammatory and autoimmune diseases, inflammatory bowel diseases, diabetes mellitus type-I and II and also progression of kidney disease. However, the relationship of vitamin D deficiency and developing of breast cancer, rheumatoid arthritis and osteoporosis is unknown. In fact, the effect of vitamin D deficiency on pathogenesis of different diseases is controversial. To cope with vitamin D deficiency, there are different recommendations such as daily intake of vitamin D supplements and more exposure to sunlight.