﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Society of Diabetic Nephropathy Prevention</PublisherName>
      <JournalTitle>Journal of Nephropharmacology</JournalTitle>
      <Issn>2345-4202</Issn>
      <Volume>8</Volume>
      <Issue>2</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2019</Year>
        <Month>05</Month>
        <DAY>01</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>Catheter related blood stream infections; the incidence and risk factors in Iranian hemodialysis patients</ArticleTitle>
    <FirstPage>e17</FirstPage>
    <LastPage>e17</LastPage>
    <ELocationID EIdType="doi">10.15171/npj.2019.17</ELocationID>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Amirhesam</FirstName>
        <LastName>Alirezaei</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0001-9720-6723</Identifier>
      </Author>
      <Author>
        <FirstName>Nilofar</FirstName>
        <LastName>Massoudi</LastName>
      </Author>
      <Author>
        <FirstName>Elham</FirstName>
        <LastName>Zare</LastName>
      </Author>
      <Author>
        <FirstName>Yasser</FirstName>
        <LastName>Nouri</LastName>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">10.15171/npj.2019.17</ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2019</Year>
        <Month>03</Month>
        <Day>17</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2019</Year>
        <Month>05</Month>
        <Day>04</Day>
      </PubDate>
    </History>
    <Abstract>Introduction: Patients with end-stage renal disease (ESRD) are routinely managed by hemodialysis. The catheter-related blood stream infections (CRBSIs) are important complications with high risk of mortality and morbidity in patients undergoing hemodialysis. Objectives: To determine the incidence of CRBSIs in patients undergoing hemodialysis in a single center in Iran. Patients and Methods: In this cross-sectional study, we evaluated the incidence of CRBSIs in 50 hemodialysis patients hospitalized at the Shahid-Modarres hospital of Tehran from March 2017 until March 2018. The data was collected from patients’ medical archives. The CRBSI was established by blood culture. Results: Of 50 hemodialysis patients enrolled in the study, 27 were males (54%). The mean age was 49.7 ±11. 8 years old. Positive blood culture was observed in 64% of patients. The most common causative organism was coagulase-negative staphylococci (24%). The most common comorbidity and systemic clinical symptom included hypertension (84%) and fever (92%) respectively. In most patients (74%), the length of catheter indwelling was less than one year. Echocardiography showed that 24% of the patients had vegetation. Conclusion: The coagulase-negative staphylococci were the most frequent organisms responsible for CRBSIs among hemodialysis patients. These findings might be helpful in early diagnosis and choose the best antibiotics for treatment. </Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">Hemodialysis</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Renal failure</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Catheter-related infections</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Staphylococcus</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Renal failure</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">End-stage renal disease</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>