Hamid Nasri
1, Mahmoud Rafieian-Kopaei
2*1 Department of Internal Medicine, Shahrekord University of Medical Sciences, Iran
2 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding Author: *Corresponding author: Prof. Mahmoud Rafieian-kopaei, Medical Plants Research Center, Shahrekord University of Medical Sciences, Sharekord, Iran., Email:
rafieian@yahoo.com
Abstract
It is well found that the assessment of circulating 25-hydroxyvitamin D offers better information about vitamin D status in patients. This cross-sectional study was aimed to better understand the probable difference of 25-hydroxyvitamin D level in a group of hemodialysis (HD) patients with or without diabetes. 25-hydroxyvitamin D level (normal range of values is 25 to 125 nmol/L) was measured following an overnight fasting. The study was conducted on 36 subjects (15 female, 21 male), consisting of 25 (female=11, male=14) non-diabetic HD patients and 11 (female=4, male=7) diabetic HD patients. A significant difference of serum 25-hydroxyvitamin D level between diabetic and non-diabetic male HD patients with more values of 25-hydroxyvitamin D level in none-diabetic HD patients was found (r=0.014). Least studied was conducted on the influence of diabetes on 25-hydroxyvitamin D level in HD patients, lower vitamin D level in diabetes patients may aggravates their condition. Thus, further investigations need to define this aspect of hemodialysis patients.
Implication for health policy/practice/research/medical education:
In a study on 36 stable hemodialysis patients, we found a low serum 25-hydroxyvitamin D in diabetic male patients in comparison to non-diabetic males. Further investigations need to define this aspect of hemodialysis patients.
Please cite this paper as: Nasri H, Rafieian-Kopaei M. Significant difference of serum 25-hydroxyvitamin D level in male hemodialysis patients with our without diabetes; a single center study. J Nephropharmacol. 2012; 1(2): 15–16.