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ePublished: 01 Jul 2012
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J Nephropharmacol. 2012;1(2): 23-26.
  Abstract View: 9696
  PDF Download: 4955

Brief Communication

Correlation of serum leptin with levels of hemoglobin in hemodialysis

Mahmoud Rafieian-Kopaei 1*, Hamid Nasri 2

1 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Section of Hemodialysis, Shahrekord University of Medical Sciences, Iran
*Corresponding Author: *Corresponding author: Prof. Mahmoud Rafieian-Kopaei, Medical Plants Research Center, Shahrekord University of Medical Sciences, Sharekord, Iran., Email: rafieian@yahoo.com

Abstract

To examine the association of serum leptin level with anemia in hemodialysis, we investigated 36 patients (males: 21, diabetics: 11) under regular hemodialysis. For patients, complete blood counts, iron profile, serum leptin, and adequacy of hemodialysis were assessed. In this study a significant correlation of serum leptin with level of hemoglobin and body mass index was detected. An association between serum leptin and total iron binding capacity was observed. No correlation of serum ferritin with leptin level was seen. Our findings attest previous findings showing that greater serum leptin levels are associated with greater hemoglobin levels.

Implication for health policy/practice/research/medical education:

In a study on 36 hemodialysis patients, we observed a positive correlation between serum leptin level and body mass index and hemoglobin, which supports the theory of a reverse epidemiological role for leptin in regular hemodialysis patients.

Please cite this paper as: Rafieian-Kopaei M, Nasri H. Correlation of serum leptin with levels of hemoglobin in hemodialysis. J Nephropharmacol 2012; 1(2): 23-26 .

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