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ePublished: 01 Jul 2013
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J Nephropharmacol. 2013;2(2): 27-30.
  Abstract View: 9742
  PDF Download: 3693

Mini-Review

Contrast induced nephropathy; recent findings

Saeed Mardani 1, Parto Nasri 2, Maryam Tavakoli 3*

1 Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding Author: *Corresponding author: Maryam Tavakoli, MD, Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran., Email: drmta2020@gmail.com

Abstract

Contrast induced nephropathy is one cause of acute renal failure. Contrast induced nephropathy is the third most common cause of hospital-acquired acute renal failure. The incidence of contrast induced nephropathy in the general population is 0.6% to 2.3%, but when focusing on specific high-risk patients the incidence can increase to more than 40%. Studies suggest that intravenous hydration is the most effective strategy to prevent contrast induced nephropathy. Hydration is inexpensive and is usually risk-free. Administration of optimal fluids before and after the contrast procedure allows for increased urine output and improved outcomes.

Implication for health policy/practice/research/medical education:

Contrast induced nephropathy is one cause of acute renal failure. Contrast induced nephropathy is the third most common cause of hospital-acquired acute renal failure. The incidence of contrast induced nephropathy in the general population is 0.6% to 2.3%, but when focusing on specific high-risk patients the incidence can increase to more than 40%. Studies suggest that intravenous hydration is the most effective strategy to prevent contrast induced nephropathy. Hydration is inexpensive and is usually risk-free. The goal of prevention is to protect the renal tubules from prolonged contact with contrast material, because permanent damage can occur at the time of contact. Administration of optimal fluids before and after the contrast procedure allows for increased urine output and improved outcomes.

Please cite this paper as: Mardani S, Nasri P, Tavakoli M. Contrast induced nephropathy; recent findings. J Nephropharmacol 2013; 2(2): 27-30.

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