Majid Tavafi
1*1 Department of Anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran
Implication for health policy/practice/research/medical education:
Major renal injuries follow ischemia reperfusion take place in two steps: one, ischemia (hypoxia) that induce ATP depletion and leads to epithelial tubular cells or endothelial cells injuries; and second, reperfusion that leads to oxidative stress, nitrosative stress and inflammation.
Please cite this paper as: Tavafi M. Suggestions for attenuation of renal ischemia reperfusion injury based on mechanisms involved in epithelial cells damages. J Nephropharmacol 2015; 4(1): 1-3.