Vibha Gupta
1*, Shahbaj Ahmad
2, Harish Chandra
1, Vikas Shrivastava
11 Department of Pathology, Himalayan Institute Medical Sciences, Swami Ram Nagar, Dehradun, India
2 Department Nephrology, Himalayan Institute Medical Sciences, Swami Ram Nagar, Dehradun, India
*Corresponding Author: *Corresponding author: Vibha Gupta, Department of Pathology, Himalayan Institute Medical Sciences, Swami Ram Nagar, Dehradun, India. , Email:
pathodoc.vibha@gmail.com
Abstract
The phenomenon of platelet satellitism (PS) is characterized by formation of platelet rosettes around polymorphonuclear leukocytes. We present a case of chronic Kidney disease that developed PS after second cycle of dialysis. A group of experiments have been conducted that suggested that contrary to common belief, anticoagulant does not play any role. In view of available literature we suggest that this phenomenon could be related to either or both of the hemodynamic stress and biocompatibility of the dialysis membrane.
Implication for health policy/practice/research/medical education:
The phenomenon of platelet satellitism (PS) is characterized by formation of platelet rosettes around polymorph- nuclear leukocytes. We suggest that this phenomenon could be related to either or both of the hemodynamic stress and biocompatibility of the dialysis membrane.
Please cite this paper as: Gupta V, Ahmad S, Chandra H, Shrivastava V. Platelet Satellitism in chronic renal failure: an experimental study. J Nephropharmacol 2015; 4(1): 13-15.