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J Nephropharmacol. 2017;6(1): 21-22.
PMID: 28197526
PMCID: PMC5295654
  Abstract View: 9354
  PDF Download: 5380

Epidemiology and Prevention

Indinavir and atazanavir; comparison of predicted property by chemoinformatics technique and implication on renal problem in HIV infected patients

Beuy Joob 1*, Viroj Wiwanitkit 2

1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Visiting Professor, Hainan Medical University, Haikou, China ; Visiting Professor, Faculty of Medicine, University of Nis, Serbia; adjunct professor, Joseph Ayobabalola University, Nigeria; Honorary Professor, Dr DY Patil Medical University, India
*Corresponding Author: *Corresponding author: Beuy Joob, , Email: beuyjoob@hotmail.com

Implication for health policy/practice/research/medical education:

Anti-HIV medication is the standard treatment for the HIV infected patient. An important concern of anti-HIV drug use is the adverse effects. The kidney problems due to anti-HIV is widely mentioned. Indinavir and atazanavir are the two drugs with many reports on renal toxicity. Here, the authors use the standard chemoinformatics technique for predicting properties of both drug and compare the derived result. Based on this study, atazanavir seems to be more problematic than indinavir considering the induction of renal problem.

Please cite this paper as: Joob B, Wiwanitkit V. Indinavir and atazanavir; comparison of predicted property by chemoinformatics technique and implication on renal problem in HIV infected patients. J Nephropharmacol. 2017;6(1):21-22.

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Abstract View: 9355

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