Paniz Pourpashang
1,2* 
1 Department of Pediatric Nephrology, Bahrami Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2 Pediatric Chronic Kidney Disease Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Abstract
The International IgA Nephropathy Prediction Tool (IgAN-PT) aims to provide individualized risk assessments for patients diagnosed with primary IgAN, which is a prevalent cause of kidney disease, especially among young adults. This tool helps clinicians to understand the risk for worsening kidney function over a period of 5-7 years post-diagnosis. This scoring can be conducted by the physician at the time of diagnosis, while it requires only routine clinical data, laboratory results, and biopsy findings. This system also is applicable to adults and pediatrics of all ethnicities.
Implication for health policy/practice/research/medical education:
The International IgA Nephropathy Prediction Tool (IgAN-PT) is a noteworthy development to assess the risk of IgA nephropathy development. This tool developed in 2018 and was designed to predict the likelihood of a 50% decline in renal function or progression to renal insufficiency based on clinical and histopathological markers at the time of kidney biopsy. The impact of this tool extends beyond mere risk prediction; since it serves as a pivotal resource for clinicians striving to personalize treatment and management strategies in IgAN too.
Please cite this paper as: Pourpashang P. Application of the updated international IgA nephropathy prediction tool in pediatric patients. J Nephropharmacol. 2025;14(2):e12800. DOI: 10.34172/npj.2025.12800.