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Submitted: 09 Apr 2026
Revision: 18 May 2026
Accepted: 19 May 2026
ePublished: 25 May 2026
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J Nephropharmacol. Inpress.
doi: 10.34172/npj.12874
  Abstract View: 8

Original

One-year survival analysis and clinical outcomes of kidney transplant recipients; an observational cross-sectional study

Mahda Iliae 1 ORCID logo, Hossein Aarafi 1 ORCID logo, Hossien Fallahzadeh 2 ORCID logo, Ahmad Shajari 1* ORCID logo

1 Department of Medicine, YMS. C., Islamic Azad University, Yazd, Iran
2 Department of Biostatistics and Epidemiology, Research Center for Healthcare Data Modeling, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
*Corresponding Author: Ahmad Shajari, Email: dr.shajari@iau.ac.ir

Abstract

Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD), offering improved survival and quality of life compared to dialysis; however, postoperative complications and short-term outcomes remain important concerns.

Objectives: This study aimed to evaluate 1-year survival and clinical outcomes among kidney transplant recipients.

Materials and Methods: In this observational cross-sectional study, we reviewed the records of 101 adult patients with ESRD who underwent kidney transplantation at Shahid Sadoughi hospital between April 2015 and March 2019. Demographic and baseline clinical data, pre-transplant dialysis modality, donor source, and etiology of kidney failure were extracted from hospital and transplant clinic files, along with postoperative complications and episodes of virus infection during the first year after transplantation. One-year kidney transplantation–specific and overall survival were assessed using follow-up data and analyzed with Kaplan–Meier survival curves.

Results: This study included a total of 101 kidney transplant recipients with a mean age of 43.26 ± 14.28 years, most of whom had received grafts from deceased donors and undergone hemodialysis before transplantation. Postoperative complications were mainly infectious and pulmonary, although nearly half of the patients had an uncomplicated course, and opportunistic viral infections occurred in only a minority. The 1‑year kidney transplantation–specific survival was 93.1%, and the mean survival time was 11.3 ± 0.25 (95% CI: 10.8-10.81). The 1‑year overall survival was 89.1%, and the mean overall survival time was 11.47 ± 0.19 (95% CI: 11.09-11.84) months.

Conclusion: Kidney transplantation showed favorable 1-year outcomes with high graft-specific and overall survival rates, despite predominantly infectious and pulmonary complications, while many patients experienced an uncomplicated postoperative course.


Implication for health policy/practice/research/medical education:

This study indicated that postoperative kidney transplantation complications were mainly infectious and pulmonary, although nearly half of the patients had an uncomplicated postoperative course, and opportunistic viral infections were infrequent. The 1-year transplantation-specific survival rate was 93.1%, while the 1-year overall survival rate was 89.1%.

Please cite this paper as: Iliae M, Aarafi H, Fallahzadeh H, Shajari A. One-year survival analysis and clinical outcomes of kidney transplant recipients; an observational cross-sectional study. J Nephropharmacol. 2026;x(x):e12874. DOI: 10.34172/npj.12874.

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