Rahimeh Eskandarian
, Mohammad Memarian
, Samira Mehrabi Pari
* 1 Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran
Abstract
SGLT2 inhibitors, primarily used to treat diabetes, have shown potential antihypertensive effects by reducing blood pressure through mechanisms like natriuresis, diuresis, and weight loss. These medications may also improve arterial stiffness and reduce inflammation, impacting to their blood pressure-lowering properties.
Implication for health policy/practice/research/medical education:
Sodium–glucose cotransporter 2 inhibitors are a promising new class of antihypertensive agents with pleiotropic cardiorenal protective effects, making them a valuable addition to the treatment of hypertension in high-risk populations.
Please cite this paper as: Eskandarian R, Memarian M, Mehrabi Pari S. Antihypertensive effects of SGLT2 inhibitors; a letter to the editor on new concepts. J Nephropharmacol. 2024;13(2):e12700. DOI: 10.34172/npj.2024.12700.